Mirtazapine is a medication that has been used in human medicine as an antidepressant. The drug widely used in veterinary medicine due to the presence of several desirable effects, namely its significant anti-nausea, anti-vomiting and appetite stimulating properties. It has been shown to be effective in increasing weight and appetite and decreasing vomiting in cats with chronic kidney disease. However, many owners have difficulty administering pills to their cat. We believe that mirtazapine, like many other medications, could be effective when formulated as a transdermal gel that can be applied to the skin of the ear. The purpose of this study is to perform a study to document the appetite stimulation properties of the transdermal form of the drug in cats with kidney disease.
Download the client consent form and learn more about this clinical trial.
Dr. Jody Lulich at the Minnesota Urolith Center (MUC) is investigating the connection between kidney stones and chronic kidney disease in cats. If cats with radiographically or ultrasonographically diagnosed kidney stones have a kidney removed during therapy, succumb to their illness, or are humanely euthanized, we can learn a lot by evaluating the structure of the kidney. Place whole, intact kidneys (without cutting them open) in formalin. If the kidney capsule can be removed, formalin can fix the tissue more effectively, but this is not necessary. Ship them to Dr. Jody Lulich at the Minnesota Urolith Center. To receive shipping instructions so that we cover mailing cost, please email Dr. Lulich at firstname.lastname@example.org. One of the most compassionate acts we can perform as veterinarians and as cat owners is to contribute samples to scientists working to cure this disease.
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