The emergence and rapid dissemination of arboviruses and their vectors throughout the world, with potentially devastating consequences, is a reality. In the last decade there have been explosive global epidemics caused by dengue, Venezuelan equine encephalitis, Rift Valley fever, Japanese encephalitis, yellow fever, West Nile, and chikungunya viruses. The Arthropod-borne Infectious Diseases Laboratory (AIDL) is one of two longstanding research programs within the Department of Microbiology, Immunology and Pathology (MIP) that serve as cornerstones for infectious disease research and education at CSU. AIDL researchers have historically been successful in obtaining funding to define mechanisms of pathogen persistence and transmission and have developed new surveillance, control, and prevention strategies. AIDL has 25 full time researchers, including nine faculty members, who form a broadly based, interactive, multi-disciplinary research and training unit. Research programs at AIDL currently focus on arboviruses vectored by mosquitoes such as eastern, western, and Venezuelan equine encephalitis, dengue, West Nile, and La Crosse viruses. We have developed close collaborations with the CDC-DVBID unit in Fort Collins, and also have collaborative programs in Mexico and Senegal, fostering international exchange of students and faculty. We have world-class facilities that allow research with NIH Category A-C arboviruses, have CDC-USDA Select Agent approved BSL3 facilities, and have one of the largest ACL2 and ACL3 insectary complexes in the nation.