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Publications

Identification of a Novel Antiviral Inhibitor of the Flavivirus Guanylyltransferase Enzyme”
Stahla-Beek HJ, April DG, Saeedi BJ, Hannah AM, Keenan SM, Geiss BJ. J Virol. 2012 Jun 6. [Epub ahead of print]

Analysis of RNA binding by the dengue virus NS5 RNA capping enzyme.”
Henderson BR, Saeedi BJ, Campagnola G, Geiss BJ. PLoS One. 2011;6(10):e25795. Epub 2011 Oct 12. PMCID: PMC3192115

Infectious alphavirus production from a simple plasmid transfection
Steel JJ, Henderson BR, Lama SB, Olson KE, Geiss BJ. Virol J. 2011 Jul 19;8:356. PMCID: PMC3156776

A High-Throughput Screening Assay for the Identification of Flavivirus NS5 Capping Enzyme GTP-Binding Inhibitors: Implications for Antiviral Drug Development
Geiss BJ, Stahla, HJ, Hannah MJ, Gari HH, Henderson BR, Saeedi BJ, and Keenan SM.
J Biomol Screen. 2011 Sep;16(8):852-61. Epub 2011 Jul 25. PMID: 21788392

The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure.”
Issur M, Geiss BJ, Bougie I, Jean F, Despins S, Mayette J, Hobdey SE, and Bisaillon M.
RNA 2009 Dec 15(12):2340-2350PMCID: PMC2779676

Focus on Flaviviruses: Current and Future Drug Targets
Geiss BJ, Stahla H, Hannah AM, Gari HH, and Keenan SM
Future Medicinal Chemistry 2009 May 1(2):327-344 PMCID: PMC2822355

Suppression of RNA Interference Increases Alphavirus Replication and Virus-Associated Mortality in Aedes aegypti Mosquitoes
Cirimotich CM, Scott JC, Phillips AT, Geiss BJ, and Olson KE.
BMC Microbiol 2009 Mar 5;9(1):49 PMCID: PMC2660349

Analysis of Flavivirus NS5 Methyltransferase Cap Binding
Geiss BJ, Thompson AA, Andrews A, Gari HH, Sons RL, Keenan SM, and Peersen OB.
J. Mol. Bio. 2009 Feb 6:385(5):1643-54 PMCID: PMC2680092

Recombination-Ready Sindbis Replicon Expression Vectors for Transgene Expression.”
Geiss BJ, Shimonkevitz LA, Sackal CI, and Olson, KE.
Virol J. 2007 Oct 26;4(1):112 PMCID: PMC2164957