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Publications

Current h-index: Brian Geiss Google Scholar

"Development of an Electrochemical Paper-Based Analytical Device for Trace Detection of Virus Particles." 
Channon, R; Yang, Y; Feibelman, KM; Geiss, BJ; Dandy, DS; Henry, CS. Analytical Chemistry – Jun 2018 19;90(12):7777-7783​ PMID:29790331 

"Identification of small molecule inhibitors of the Chikungunya virus nsP1 RNA capping enzyme." 
Feibelman KM, Fuller BP, Li L, LaBarbera DV, Geiss BJ. Antiviral Res. 2018 Jun;154:124-131. PMID: 29680670

​"Allostery in the dengue virus NS3 helicase: Insights into the NTPase cycle from molecular simulations." 
Davidson RB, Hendrix J, Geiss BJ, McCullagh M.​ . PLoS Comput Biol. 2018 Apr 16;14(4):e1006103. PMID: 29659571

​"2'-O-methylation of the mRNA cap protects RNAs from decapping and degradation by DXO."
 
Picard-Jean F, Brand C, Tremblay-Létourneau M, Allaire A, Beaudoin MC, Boudreault S, Duval C, Rainville-Sirois J, Robert F, Pelletier J, Geiss BJ, Bisaillon M.​ . PLoS One. 2018 Mar 30;13(3):e0193804. PMID: 29601584​

​"Highly Sensitive Detection of Salmonella typhimurium Using a Colorimetric Paper-Based Analytical Device Coupled with Immunomagnetic Separation."
Srisa-Art M, Boehle KE, Geiss BJ, Henry CS. Anal Chem. 2018 Jan 2;90(1):1035-1043.​ PMID: 29211962​

"Organization of the Flavivirus RNA replicase complex."
Brand C, Bisaillon M, Geiss BJ. Wiley Interdiscip Rev RNA. 2017 Nov;8(6)​ PMID: 28815931 

"Rescue and Characterization of Recombinant Virus from a New World Zika Virus Infectious Clone." 
Weger-Lucarelli J, Duggal NK, Brault AC, Geiss BJ, Ebel GD. J Vis Exp. 2017 Jun 7;(124). PMID: 28654045​

​"Utilizing Paper-Based Devices for Antimicrobial-Resistant Bacteria Detection."
Boehle KE, Gilliand J, Wheeldon CR, Holder A, Adkins JA, Geiss BJ, Ryan EP, Henry CS. Angew Chem Int Ed Engl. 2017 Jun 6;56(24):6886-6890​ PMID: 28474847​

"A sensitive DNA capacitive biosensor using interdigitated electrodes."
Wang, L., Veselinovic, M., Yang, L., Geiss, B. J., Dandy, D. S., Chen, T. W. Biosensors and Bioelectronics. Jan 2017 15;87:646-653.​ PMID: 27619528​

"Paper-Based Microfluidic Devices: Emerging Themes and Applications."
Yang, Y., Noviana, E., Nguyen, M. P., Geiss, B. J., Dandy, D. S., Henry, C. S. Analytical chemistry. 2016 Jan 3;89(1):71-91. PMID: 27936612​

"The FDA-approved drug sofosbuvir inhibits Zika virus infection."
Bullard-Feibelman, K. M., Govero, J., Zhu, Z., Salazar, V., Veselinovic, M. S., Diamond, M. S., Geiss, B. J.  Antiviral research, 2016 137, 134-140. PMID: 27902933​

​"Development and Characterization of Recombinant Virus Generated from a New World Zika Virus Infectious Clone.​"
Weger-Lucarelli, J., Duggal, N. K., Bullard-Feibelman, K., Veselinovic, M. S., Romo, H., Nguyen, C. N., Rückert, C., Brault, A. C., Bowen, R. A., Stenglein, M. D., Geiss, B. J.*, Ebel, G. D*. Journal of virology. 2016 Dec 16;91(1). PMID: 27795432 *Co-Contributing Authors

"A Sensitive and Robust High-Throughput Screening Assay for Inhibitors of the Chikungunya Virus nsP1 Capping Enzyme.​"

Bullard-Feibelman, K. M., Fuller, B. P., Geiss, B. J. PLoS One. 2016 Jul 18;11(7):e0158923 PMID: 27427769​

"A novel system for visualizing alphavirus assembly." 
Steel JJ, Geiss BJ. Virol Methods. 2015 Sep 15;222:158-63.  PMID: 26122073​​

"Murine Efficacy and Pharmacokinetic Evaluation of the Flaviviral NS5 Capping Enzyme 2-Thioxothiazolidin-4-One Inhibitor BG-323."
Bullard KM, Gullberg RC, Soltani E, Steel JJ, Geiss BJ, Keenan SM. PLoS One.2015 Jun 15;10(6):e0130083.​ PMID: 26075394​

"Benzothiazole and Pyrrolone Flavivirus Inhibitors Targeting the Viral Helicase​."

Sweeney NL, Hanson AM, Mukherjee S, Ndjomou J, Geiss BJ, Steel JJ, Frankowski KJ, Li K, Schoenen FJ, and Frick DN.  ACS Infectious Diseases 2015 Jan 21 DOI:10.1021/id5000458 PMID: 26029739​

"Oxidative stress influences positive strand RNA virus genome synthesis and capping."​

Gullberg RC, Steel JJ, Moon SL, Soltani E, Geiss BJ.  Virology 2015 January 475(1): 219-229.  PMID: 25514423 *This manuscript was selected as a highlighted research article in Virology​.

"Subgenomic Reporter RNA System for Detection of Alphavirus Infection in Mosquitoes."
Steel JJ, Franz AWE, Sanches-Vargas I, Olson KE, Geiss BJ (2013).  PLoS ONE 8(12): e84930. DOI:10.1371/journal.pone.0084930. PMID: 24367703

"PAIRpred: Partner-specific prediction of interacting residues from sequence and structure."
Minhas FA, Geiss BJ, and Ben-Hur A. Proteins: Structure, Function, and Bioinformatics 2013 Nov 16. DOI: 10.1002/prot.24479. [Epub ahead of print] PMID: 24243399

"Regulation of flavivirus RNA synthesis and capping."
Saeedi, BJ and Geiss, BJ. WIRES RNA 2013 Aug 8 DOI: 10.1002/wrna.1191.  PMID: 23929625

"Ring around the Ro-sie:  RNA Mediated Alterations of PNPase Activity."
Geiss BJ and WIlusz J. Cell 2013 March 28; 153(1): 12-14.  PMID: 23540686

”Identification of a Novel Antiviral Inhibitor of the Flavivirus Guanylyltransferase Enzyme”
Stahla-Beek HJ, April DG, Saeedi BJ, Hannah AM, Keenan SM, Geiss BJ. J Virol. 2012 Jun 6. [Epub ahead of print] PMID: 22674988​

Analysis of RNA binding by the dengue virus NS5 RNA capping enzyme.”
Henderson BR, Saeedi BJ, Campagnola G, Geiss BJ. PLoS One. 2011;6(10):e25795. Epub 2011 Oct 12. PMCID: PMC3192115

Infectious alphavirus production from a simple plasmid transfection
Steel JJ, Henderson BR, Lama SB, Olson KE, Geiss BJ. Virol J. 2011 Jul 19;8:356. PMCID: PMC3156776

A High-Throughput Screening Assay for the Identification of Flavivirus NS5 Capping Enzyme GTP-Binding Inhibitors: Implications for Antiviral Drug Development
Geiss BJ, Stahla, HJ, Hannah MJ, Gari HH, Henderson BR, Saeedi BJ, and Keenan SM. J Biomol Screen. 2011 Sep;16(8):852-61. Epub 2011 Jul 25. PMID: 21788392

The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure.”
Issur M, Geiss BJ, Bougie I, Jean F, Despins S, Mayette J, Hobdey SE, and Bisaillon M. RNA 2009 Dec 15(12):2340-2350PMCID: PMC2779676

Focus on Flaviviruses: Current and Future Drug Targets
Geiss BJ, Stahla H, Hannah AM, Gari HH, and Keenan SM. Future Medicinal Chemistry 2009 May 1(2):327-344 PMCID: PMC2822355

Suppression of RNA Interference Increases Alphavirus Replication and Virus-Associated Mortality in Aedes aegypti Mosquitoes
Cirimotich CM, Scott JC, Phillips AT, Geiss BJ, and Olson KE. BMC Microbiol 2009 Mar 5;9(1):49 PMCID: PMC2660349

Analysis of Flavivirus NS5 Methyltransferase Cap Binding
Geiss BJ, Thompson AA, Andrews A, Gari HH, Sons RL, Keenan SM, and Peersen OB. J. Mol. Bio. 2009 Feb 6:385(5):1643-54 PMCID: PMC2680092

Recombination-Ready Sindbis Replicon Expression Vectors for Transgene Expression.”
Geiss BJ, Shimonkevitz LA, Sackal CI, and Olson, KE. Virol J. 2007 Oct 26;4(1):112 PMCID: PMC2164957

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