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Kenneth E. Olson: Research

 

 Olson Laboratory Information

 

Viral Zoonoses: Development of a Novel Antiviral Therapy Targeting Multiple Alphaviruses

Dates: 2009 - 2015
Sponsor: NIH Regional​ Center for Excellence for Biodefense and Emerging Infectious Diseases
Principal Investigator:
Kenneth E. Olson
Subproject: RP 003/004

New Alphavirus Expression Systems for Mosquitoes

Dates: 2009 - 2014
Sponsor: National Institutes of Health
Type: RO1 NIH AI-46435
Principal Investigator: Kenneth E. Olson
The major goal of this project is to identify molecular determinants of Sindbis virus infection in Aedes mosquitoes and develop new Sindbis virus-based expression systems for transient gene expression in mosquitoes.

Yellow Fever/Dengue Virus Competence in Aedes Aegypti Aegypti/Formosus in Senegal

Dates: 2009 - 2014
Sponsor: National Institutes of Health
Type: NIH-NIAID R01
Principal Investigator: William C. Black IV
Co-PI: Kenneth E. Olson
The goal of this grant is to elucidate genetic differences between two subspecies of Aedes aegypti that may shed light on genetic factors influencing vector competence for flaviviruses.

Molecular Mosquitocides: Development of an Innovative and Robust, Platform-Based Approach for Sustainable Insecticidal Control of Anopheline Mosquitoes

Dates: 2011 - 2015
Sponsor: National Institutes of Health
Type: FNIH
Principal Investigator: Kenneth E.
Olson
The major goals of this are to identify, characterize and optimize candidate genes and specific target ASs for MMs, 2) adapt and optimize nanoparticles for MM packaging and delivery, 3) determine stability and lethality of MMs, and 4) determine the control efficacy of MM candidates.

MIP Bridge Grant Funding

Dates: 2014 - 2015
Sponsor: Microbiology, Immunology, and Pathology Department at Colorado State University
The goals of this grant are to identify the extent of neurodegeneration in the basal ganglia of mice following intranasal infection of luciferase-expressing western equine encephalitis virus. We also will measure the effect of antibody-mediated antiviral activity in mice by in vitro intracellular calcium ion concentration and oxidative stress assays.

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