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Refereed Publications

Aigner T., Cook J., Gerwin N., Glasson S., Laverty S., Little C.B., McIlwraith C.W., Kraus V.B. Histopathology atlas of animal model systems – overview of guiding principles. Osteoarthritis Cartilage 2010;18 (Suppl 3):S2-S6.
 
Ayturk U., Puttlitz C.M. Parametric convergence sensitivity and validation of a finite element model of the human lumbar spine. Comput Methods Biomech Biomed Engin 2011;14:695-705.
 
Ayturk U., Garcia J., Puttlitz C.M. The micromechanical role of the annulus fibrosis components under physiological loading of the lumbar spine. J Biomech Eng 2010;132: 061007.
 
Ayturk U.M., Garcia J.J., Puttlitz C.M. The micromechanical role of the annulus fibrosis components under physiological loading of the lumbar spine. J Biomech Eng 2010.
 
Almodovar J., Bacon S., Gogolski J., Kisiday J., Kipper M. Polysaccharide-based polyelectrolyte multilayer surface coatings can enhance mesenchymal stem cell response to adsorbed growth factors. Biomacromolecules, 2010;11:2629-239.
 
Barrett M.F., Frisbie D.D., McIlwraith C.W., Werpy N.M. The arthroscopic and ultrasonographic boundaries of the equine femorotibial joints. Equine Vet J 2011;44:57-63.
 
Botolin S., Puttlitz C., Baldini T., Petrella A., Burger E., Abjornson C., Patel V. Facet joint biomechanics at the treated and adjacent levels after total disc replacement. Spine 2011;36:E27-32.
 
Bridge J.W., Peterson M.L., McIlwraith C.W., Beaumont R.M. Temperature effects on triaxial shear strength of granular composite sport surfaces. J ASTM International 2010;7:JAI103139.
 
Bridge J.W., Peterson M.L., Radford D.W., McIlwraith C.W. Thermal transitions in high oil content petroleum-based wax blends used in granular sport surfaces. Thermochimica Acta 2010;498:106-111.
 
Cabano N.R., Troyer K.L., Palmer R.H., Puttlitz C.M., Santoni B.G. Mechanical comparison of two suture constructs for extra-capsular stifle stabilization. Vet Surg 2011;40:334-9.
 
Carpenter R.S., Goodrich L.R., Frisbie D.D., Kisiday J.D., Carbone B., McIlwraith C.W., Centeno C.J., Hidaka C. Ostoeblastic differentiation of human and equine adult bone marrow-derived mesenchymal stem cells when BMP-2 or BMP-7 homodimer genetic modification is compared to BMP-2/7 heterodimer genetic modification in the presence and absence of dexamethasone. J Orthop Res 2010;28:1330-1337.
 
Case J.B., Palmer R., Valdes-Martinez A., Egger E.L., Haussler K.K. Gastrocnemius tendon strain in a dog treated with autologous mesenchymal stem cells and a custom orthosis. Vet Surg 2011. Submitted.
 
Cheetham J., Riordan A.S., Mohammed H.O., McIlwraith C.W., Fortier L.A. Relationships between race earnings and horse age, sex, gait, track surface, and number of race starts for Thoroughbred and Standardbred racehorses in North America. Equine Vet J 2010;42:346-350.
 
Contino E.K., Park R.D., McIlwraith C.W. Prevalence of radiographic changes in yearling and 2-year-old Quarter Horses intended for cutting. Equine Vet J 2011. In Press.
 
Cook J.L., Evans R., Conzemius M.G., Lascelles B.D.X., McIlwraith C.W., Pozzi A., Clegg P., Inhes J., Schulz K., Houlton J., Fortier L., Cross A.R., Hayashi K., Kapatkin A., Brown D.C., Stewart A. Proposed definitions and criteria for reporting time frame, outcome, and complications for clinical orthopedic studies in veterinary medicine. Vet Surg 2010;39:905-908.
 
Corbin L.J., Blott S.C., Swinburne J.E., Sibbons C., Fox-Clipsham L.Y., Helwegen M., Parkin T.D., Newton J.R., Bramlage L.R., McIlwraith C.W., Bishop S.C., Woolliams J.A., Vaudin M. A genome-wide association study of osteochondrosis dissecans in the Thoroughbreds 2011. In Press.
 
Damodaran V.B., Fee C.J., Popat K.C. Prediction of protein interaction behaviour with PEG grafted matrices using X-ray photoelectron spectroscopy. Appli Surf Sci 2010;256:4894-3501.
 
Damodaran V.B., Fee C.J., Ruckh T.T., Popat K.C. Conformational studies of covalently grafted poly(ethylene glycol) on modified solid matrices using X-ray photoelectron spectroscopy. Langmuir 2010;26:7299-7306.
 
Ehlen K., Reiser R., Browning R. Energetics and biomechanics of inclined treadmill walking in obese adults. Med Sci Sports Exer 2011;43:1251-1259.
 
Ferris D.J., Frisbie D.D., Kisiday J.D., McIlwraith C.W. In vivo healing of meniscal lacerations using bone marrow derived mesenchymal stem cells and fibrin glue. Stem Cell International 2011. In Press.
 
Ferris D.J., Frisbie D.D., McIlwraith C.W., Kawcak C.E. Current joint therapy usage in equine practice: a survey of veterinarians 2009. Equine Vet J 2011;43:530-535.
 
Firth E.C., Rogers C.W., van Weeren P.R., Barneveld A., McIlwraith C.W., Kawcak C.E., Goodship A.E., Smith R.K.W. Mild exercise early in life produces changes in bone size and strength but not density in proximal phalangeal, third metacarpal and third carpal bones in foals. Vet J 2011. In Press.
 
Firth E.C., Rogers C.W., van Weeren P.R., Barneveld A., McIlwraith C.W., Kawcak C.E., Goodship A.E., Smith R.K.W. The effect of previous conditioning exercise on diaphyseal and metaphyseal bone to imposition and withdrawal of training in young Thoroughbred horses. Vet J 2011. In Press.
 
Frisbie D.D., McIlwraith C.W., Arthur R.M., Blea J., Baker V.A., Billinghurst R.C. Serum biomarker levels for musculoskeletal disease in 2 and 3 year-old racing Thoroughbred horses: A prospective study of 130 horses. Equine Vet J 2010;42:643-651.
 
Frisbie D.D., Smith R.K.W. Clinical update on the use of mesenchymal stem cells in equine orthopaedics. Equine Vet J 2010;42:86-89.
 
Gutierrez S.D., White N.A., Werpy N.M. Outcome of medical treatment for horses with foot pain: 56 cases. Equine Vet J 2010;42:680-685.
 
Hackett E.S., Harilal D., Bowley C., Hawes M., Turner A.S., Goldman S.M. Evaluation of porcine hydrated dermis augmented repair in a fascial defect model, J. Biomed. Mater. Res Part B – Applied Biomat 2011;96B: 134-138.
 
Hale B.W., Goodrich L.R.; Frisbie D.D., McIlwraith C.W., Kisiday J.D. Effect of scaffold dilution on mesenchymal stem cell migration from fibrin hydrogels. Am J Vet Res 2011. In Press.
 
Harrison S.M., Whitton R.C., Kawcak C.E., Stover S.M., Pandy M.G. Relationship between muscle forces, joint loading and utilization of elastic strain energy in equine locomotion. J Exp Biol 2010;213:3998-4009.
 
Haussler K.K. The role of manual therapies in equine pain management. Submitted to the Veterinary Clinics of North America: Equine Practice. Guest Editor: Muir W.W. May 2010.
 
Hee C.K., Dines J.S., Roden C.M., Wisner-Lynch L.A., Turner A.S., McGilvaray K.C., Lyons A.S., Puttlitz C.M., Santoni B.G. Augmentation of a rotator cuff repair using rhPDGF-BB and a type I bovine collagen matrix in an ovine model. Am J Sports Med 2011;39:1630-9.
 
Hendrix S.M., Baxter G.M., McIlwraith C.W., Hendrickson D.A., Goodrich L.R., Frisbie D.D., Trotter G.W. Combination of meniscal and subchondral cystic lesions within the medial femorotibial joints in horses (1996-2006). Equine Vet J 2010;42:5-429.
 
Henson V.M.D., Getgood A., Caborn D., McIlwraith C.W., Rushton N. The effect of hyaluronic acid/chondroitin sulfate/N-acetyl glucosamine preparation on the response of cartilage to single impact load damage/repair – a preliminary report. Am J Vet Res 2011. In Press.
 
Hraha T.H., Doremus K.M., McIlwraith C.W., Frisbie D.D. Autologous conditioned serum: The comparative cytokine profiles of two commercial methods (IRAP and IRAP II) using equine blood. Equine Vet J 2011;43:516-521.
 
Hurtig M.B., Buschmann M.D., Fortier L.A., Hoemann C.D., Hunziker E.B., Jurvelin J.S., Mainil-Varlet P., McIlwraith C.W., Sah R.L., Whiteside R.A. Preclinical studies for cartilage repair: Recommendations from the International Cartilage Repair Society. Cartilage 2011;2:137-152.
 
Jalim S., McIlwraith C.W., Anderson G. Lag screw fixation of dorsal cortical stress fractures of the third metacarpal bone in 116 racehorses. Equine Vet J 2010;42:586-590.
 
Kawcak C.E., Frisbie D.D., McIlwraith C.W. Effects of extracorporeal shock wave therapy and polysulfated glycosaminoglycan treatment on subchondral bone, serum biomarkers and synovial fluid biomarkers in horses with induced osteoarthritis. Am J Vet Res 2011;72:772-779.
 
Kawcak C.E., McIlwraith C.W. Comparison of synovial fluid in middle carpal joints undergoing needle aspiration, infusion with saline and infusion with a combination of n-acetyl-D-glucosamine, hyaluronic acid and sodium chondroitin sulfate. J Equine Vet Sci 2011;31:155-159.
 
Kawcak C.E., McIlwraith C.W., Firth E. Effects of early exercise on metacarpophalangeal joints in horses. Am Vet J Res 2010;71:405-411.
 
Kim W., Kawcak C.E., McIlwraith C.W., Firth E.C., Broom N.D. Early exercise and lesion development in the equine midcarpal joint: a detailed structural and histomorphometric study. Am J Vet Res 2011. In Press.
 
Kisiday J.D., Hale B.W., Almodovar J.L., Lee C.M., McIlwraith C.W., Frisbie D.D. Expansion of mesenchymal stem cells on fibrinogen-rich protein surfaces derived from blood plasma. J Tissue Eng Regen Med 2011;5:600-611.
 
Kisiday J.D., Lee C.M., McIlwraith C.W., Frisbie D.D. Induction of bone marrow mesenchymal stem cell chondrogenesis following short-term suspension culture. J Orthop Res 2011;29:26-32.
 
Kisiday J.D., McIlwraith C.W., Frisbie D.D., Rodkey W.R. Evaluation of the effect of single and double spin preparations of platelet rich plasma on anabolic and catabolic activities of cartilage and meniscal explants in vitro. Cartilage 2011. In Press.
 
Kisiday J.D., Vanderploeg E.J., McIlwraith C.W., Grodzinsky A.J., Frisbie D.D. Mechanical injury of explants from the articulating surface of the inner meniscus. Archives Biochem Biophysics 2010;494:138-144.
 
Kopesky P.W., Vanderploeg E.J., Kisiday J.D., Frisbie D.D., Sandy J.D., Grodzinsky A.J. Controlled delivery of Transforming Growth Factor β1 by self-assembling peptide hydrogels induces chondrogenesis of bone marrow stromal cells and modulates Smad2/3 signaling. Tissue Eng Part A 2011;17:83-92.
 
Kopesky P.W., Lee H.Y., Vanderploeg E.J., Kisiday J.D., Frisbie D.D., Plaas A.H.K., Ortiz C., Grodzinsky A.J. Adult equine bone marrow stromal cells produce a cartilage-like ECM mechanically superior to animal-matched adult chondrocytes. Matrix Bio 2010;29:427-438.
 
Leahy P.D., Smith B.S., Easton K.L., Kawcak C.E., Eickhoff J.C., Shetye S.S., Puttlitz C.M. Correlation of mechanical properties within the equine third metacarpal with trabecular bending and multi-density micro-computed tomography data. Bone 2010;2046:1108-1113.
 
Lee H.Y., Kopesky P.W., Plaas A., Sandy J., Kisiday J., Frisbie D.D., Grodzinsky A.J., Ortiz C. Adult bone marrow stromal cell-based tissue engineered aggrecan exhibits ultrastructural and nanomechanical properties superior to native cartilage. Osteoarthritis Cartilage 2010;18:1477-1486.
 
Lyons A.S., Sherman B.P., Puttlitz C.M., Patel V.V., Abjornson C., Turner A.S., Seim H.B. III, Burger E.L., Lindley E.M. Failure of resorbable plates and screws in an ovine model of anterior cervical discectomy and fusion. Spine J 2011;11:876-883.
 
Maher M.C., Werpy N.M., Goodrich L.R., McIlwraith C.W. Positive contrast magnetic resonance bursography for assessment of the navicular bursa and surrounding soft tissues. Vet Radiol Ultrasound 2011;52:385-393.
 
McGilvray K.C., Santoni B.G., Turner A.S., Bogdansky S., Wheeler D.L., Puttlitz C.M. Effects of 60CO gamma irradiation dose on initial structural biomechanical properties of ovine bone – patellar tendon – bone allografts. Cell Tissue Bank 2011;12:89-98.
 
McGilvray K.C., Sariar R., Nguyen K., Puttlitz C.M. A biomechanical analysis of venous tissue in its normal and post-phlebitic conditions. J Biomech 2010;43:2941-7.
 
McIlwraith C.W., Frisbie D.D., Rodkey W.G., Kisiday J.D., Werpy N.M., Kawcak C.E., Steadman J.R. Evaluation of intra-articular mesenchymal stem cells to augment healing of microfractured chondral defects. Arthroscopy 2011;27:1552-1561.
 
McIlwraith C.W., Frisbie D.D., Kawcak C.E. Evaluation of intramuscularly administered sodium pentosan polysulfate for treatment of horses with experimentally induced osteoarthritis. Am J Vet Res 2011. In Press.
 
McIlwraith C.W., Fortier L.A., Frisbie D.D., Nixon A.J. Equine models of articular cartilage repair. Cartilage 2011;2:317-326.
 
McIlwraith C.W. Management of subchondral cystic lesions of medial femoral condyle – an evolution based on research and clinical evidence. Pferdeheilkunde 2010;26:591-597.
 
McIlwraith C.W. The use of intra-articular corticosteroids in the horse – What do we know on a scientific basis? Equine Vet J 2010;42:563-571.
 
McIlwraith C.W., Frisbie D.D. Microfracture: Basic science studies in the horse. Cartilage 2010;1:87-95.
 
McIlwraith C.W., Frisbie D.D., Kawcak C.E., Fuller C.J., Hurtig M., Cruz A. The OARSI histopathology initiative – recommendation for histological assessments of osteoarthritis in the horse. Osteoarthritis Cartilage 2010;18(Suppl 3):S95-S105.
 
McIlwraith C.W., Frisbie D.D., Kawcak C.E., Fuller C.J., Hurtig M., Cruz A., Aigner T. Recommendation of criteria for the evaluation of macroscopic and histological changes occurring in equine osteoarthritis. Osteoarthritis Cartilage 2010;18:S95-S105.
 
Melik R., Unal E., Perkgoz N., Puttlitz C., Demir H.V. Metamaterial-based telemetric strain sensing in different materials. Optic Express 2010;18:5000-7.
 
Melik R., Unal E., Perkgoz N., Santoni B., Kamstock D., Puttlitz C., Demir H.V. Nested metamaterials for wireless strain sensing. IEEE Journal of Selected Topics in Quantum Electronics 2010;16:450-8.
 
Merrit J.S., Pandy M.G., Brown N.A.T., Burvill C.R., Kawcak C.E., McIlwraith C.W., Davies H.M.S. Mechanical loading of the distal end of the third metacarpal bone in horses during walking and trotting. Am J Vet Res 2010;71:508-514.
 
Miller R.E., Grodzinsky A.J., Vanderploeg E.J., Lee C., Ferris D.J., Barrett M.F., Kisiday J.D., Frisbie D.D. Repair of Full-Thickness Articular Cartilage Defect Using Self-Assembling Peptide, Chondrogenic Factors, and Bone Marrow Derived Stromal Cells on osteochondral repair. Osteoarthritis Cartilage 2010;18:1608-1619.
 
Moorman V.J., Reiser R.F., McIlwraith C.W., Kawcak C.E. Validation of an equine inertial measurement unit system in normal horses over-ground at the walk and trot. Am J Vet Res 2011. In Press.
 
Oldinski R.A., Ruckh T.T., Staiger M.P., Popat K.C., James S.P. Dynamic mechanical analysis and biomineralization of hyaluronan–polyethylene copolymers for potential use in osteochondral defect repair. Acta Biomater 2011;7:1184-1191.
 
Peterson M., Reiser R., Kuo P.H., Radford D., McIlwraith C.W. Effect of temperature on race time on a synthetic surface. Equine Vet J 2010;42:351-357.
 
Pearce G.L., Frisbie D.D. Statistical Evaluation of Biomedical Studies. Osteoarthritis Cartilage 2010;18 (Suppl 3):S117-122.
 
Reed S.R., Jackson B.F., McIlwraith C.W., Wright I.M., Pilsworth R., Knapp S., Wood J.L.N., Price J.S., Verheyen K.L.P. Descriptive epidemiology of joint injuries in Thoroughbred racehorses in training. Equine Vet J 2011. In Press.
 
Ruckh T.T., Kumar K., Kipper M.J., Popat K.C. Osteogenic differentiation of bone marrow stromal cells on poly (e-caprolactone) nanofiber scaffolds. Acta Biomater 2010;6:2949-2959.
 
Samuel L., Judson B.A., Popat K.C. Template synthesized poly (e-caprolactone) nanowire surfaces for neural tissue engineering. Biomat 2010;31:3492-3501.
 
Santoni B.G., McGilvray K.C., Lyons A.S., Bansal M., Turner A.S., MacGilvray J.D., Coleman S.H., Puttlitz C.M. Biomechanical analyses of an ovine rotator cuff repair via porous patch augmentation in a chronic rupture model. Am J Sports Med 2010;38:679-86.
 
Santoni B.G., McGilvray K.C., Lyons A.S., Bansal M., Turner A.S., Patel V.V., Puttlitz C.M. Biomechanical and kinetic testing of two-level cervical disc replacement. Minerva Ortopedica e Traumatologica 2010;61:1-9.
 
Selberg K., Werpy N.M. Fractures of the Distal Phalanx and Associated Soft Tissue and Osseous Abnormalities in 22 Horses with Ossified Sclerotic Ungual Cartilages Diagnosed with Magnetic Resonance Imaging. Vet Radiol Ultrasound 2011;52:1-8.
 
Siu R.K., Lu S.S., Whang J., McNeill G., Zhang X., Wu B.M., Turner A.S., Seim H.B. III, Wang J., Gertzman A., Ting K., Soo C. Purified Nell-1 protein promotes bone formation in a sheep spinal fusion model. Tiss Eng Part A 2011;17:1123-1135.
 
Smith R.K., McIlwraith C.W. Consensus on equine tendon disease: Building on the 2007 Havemeyer symposium. Equine Vet J 2011. In Press.
 
Smith B.S., Yoriya S., Grissom L., Grimes C.A., Popat K.C. Hemocompatibility of titania nanotube arrays. J Biomed Mat Res A 2010;95A:350-260.
 
Stewart A.A., Goodrich L.R., Byron C.R., Evans R.B., Stewart M.C. Antimicrobial delivery by intrasynovial catheterization in equine synovial trauma and sepsis cases: a description of the technique and outcome of 38 cases. Aust Vet J 2010;88:115-23.
 
Timothy T. Ruckh, Kuldeep Kumar, Matthew J. Kipper, Ketul C. Popat. "Osteogenic differentiation of bone marrow stromal cells on poly(e-caprolactone) nanofiber scaffolds," Acta Biomaterialia 2010;6:2949-2959.
 
Troyer K.L., Estep D.J., Puttlitz C.M. Viscoelastic effects during loading play an integral role in soft tissue mechanics. Acta Biomater 2011;7:700-09.
 
Troyer K., Puttlitz C.M. Human cervical spine ligaments exhibit fully nonlinear viscoelastic behavior. Acta Biomaterialia 2011;7:700-09.
 
Van Lanen N., Franklin A., Huyvaert K., Reiser R., Carlson P. Who hits and hoots at whom? Potential for interference competition between barred and northern spotted owls. Biol Conser 2011;144:2194-2201.
 
Van Weeren P.R., McGowan C., Haussler K.K. Development of a structural and functional understanding of the equine back. Equine Vet J 2010;42(Suppl 38):393-400.
 
Wagner A., Khursheed M., Contino E., Ferris D., Kawcak C.E. Evaluation of standing sedation in horses using xylazine, butorphanol, and subanesthetic doses of ketamine. J Am Vet Med Assoc 2011. In Press.
 
Werpy N.M., Ho C.P., Pease A.P., Kawcak C.E. The effect of sequence selection and field strength on detection of osteochondral defects in the metacarpophalangeal joint. Vet Radiol Ultrasound 2011;52:154-60.
 
Werpy N.M., Ho C.P., Pease A.P., Kawcak C.E. Detection of Osteochondral defects in the fetlock using low and high field strength magnetic resonance imaging. Vet Radiol Ultrasound 2011;52:154-160.
 
Werpy N.M., Ho C.P., Kawcak C.E. Magic angle effect in normal collateral ligaments of the distal interphalangeal joint in horses imaged with a high-field magnetic resonance imaging system. Vet Radiol Ultrasound 2010;51:2-10.
 
Wilson D., Ehrhart N.P., Santoni B.S. Biomechanical comparison of the 3.5 mm broad limited contact dynamic compression plate and the 3.5 mm broad locking compression plate. Vet Surg, 2010, In Press.
 
Woldtvedt D.J., Womack W., Gadomski B.C., Schuldt D., Puttlitz C.M. Finite element lumbar spine facet contact parameter predictions are affected by the cartilage thickness distribution and initial joint gap size. J Biomech Eng 2011;133:061009.
 
Womack W., Leahy P.D., Patel V.V., Puttlitz C.M. Finite element modeling of kinematic and load transmission alterations due to cervical disc replacement. Spine 2011;36:E126-33.
 
Womack W., Ayturk U.M., Puttlitz C.M. Cartilage thickness distribution affects computational model predictions of facet contact parameters. J Biomech Eng 2011;133:011009.
 
Wong B.L., Kim S.H.C., Antonacci J.M., McIlwraith C.W., Sah R.L. Cartilage shear dynamics during tibio-femoral articulation: effect of acute joint injury and tribosupplementation on synovial fluid lubrication. Osteoarthritis Cartilage 2010;18:464-471.
 
Zoppa A.L., Santoni B., Puttlitz C.M., Cochran K., Hendrickson D.A. Arthrodesis of the equine proximal interphalangeal joint: A biomechanical comparison of three-hole 4.5 mm locking compression plate and three-hole 4.5 mm narrow dynamic compression plate with two oblique 5.5 mm cortex screws. Vet Surg 2011;40:253-9.
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