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Immunotherapy and Vaccines

Immunotherapy and Vaccines for Infectious Diseases

The research groups involved in this effort includes researchers from both the Department of Clinical Sciences and from the Department of Microbiology, Immunology, and Pathology. 

Current Studies

  • Improved vaccination for viral infections of cats
    Researchers in the Department of Clinical Sciences are developing more effective vaccination protocols to prevent viral respiratory infections of cats and to prevent viral spread amongst shelter cat populations. 
    Program faculty:  Dr. Mike Lappin, Dr. Kristy Dowers, Dr. Julia Veir
  • Immunotherapeutics for prion infection
    Faculty in the Department of Microbiology, Immunology, and Pathology are developing new immune-based approaches to treatment of CNS infection with prions, especially the chronic wasting disease (CWD) agent, using mouse models and deer infection studies. 
    Program faculty:  Dr. Mark Zabel
  • Immunotherapy for prevention of canine and feline viral upper respiratory infections
    CIRM faculty are investigating new methods of using novel immune stimulants to induce non-specific protection from highly contagious respiratory diseases of cats and dogs, including kennel cough in dogs and viral upper respiratory syndrome in cats. The goal is to develop new immunotherapies that can easily administered and induce rapid protection for young animals or animals in shelters or day care settings.
    Program faculty: Drs. Mike Lappin, Steven Dow, Jessica Quimby, William Wheat, Dan Regan

Immunotherapy And Vaccines For Cancer

The research groups involved in the Cancer Immunotherapy program include faculty from the Animal Cancer Center, the Department of Clinical Sciences, and from the Department of Microbiology, Immunology, and Pathology.
  • Cancer stem cell vaccines
    Faculty in the CIRM and the Animal Cancer Center are developing a new generation of cancer vaccines that target cancer stem cells, unlike current cancer vaccines that target primarily mature tumor cells or single antigens.  The stem cell vaccines are being tested in animal models of cancer and are close to clinical evaluation in dogs with a variety of different cancer types.
    Program faculty: Drs. Amanda Guth, Dan Regan, and Steven Dow
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