Dr. Dow is the Director of CIRM and a Professor in the Department of Clinical Sciences and in the Department of Microbiology, Immunology and Pathology. His laboratory investigates immune responses in infectious diseases, cancer, and allergic and autoimmune diseases. His laboratory is studying the immune modulatory effects of mesenchymal stem cells and the use of MSC to treat asthma in a mouse model. The Dow lab is investigating the anti-inflammatory and renotropic effects of MSC for treatment of chronic kidney disease, using a feline spontaneous chronic kidney disease model. The lab is also developing new cancer vaccines for lymphoma and other tumors in dogs. At the Infectious Disease Research Center, the Dow lab is working on developing new vaccines and immunotherapies for infection with the bacterial pathogen Burkholderia pseudomallei.