Skip Ribbon Commands
Skip to main content
Faculty & Research Members

Aimee Colbath

​Dr. Colbath is a post-DVM fellow in the Department of Clinical Sciences who is studying the use of stem cells for cartilage repair and osteoarthritis in horses, in conjunction withe the laboratory of Dr. Laurie Goodrich. She is currently studying techniques for generating equine iPSC cells and then introducing these cells to become cartliage producing cells. She is also studying the immune modulary effects of mesenchymal stem cells in the equine joint.

Dr. Dow is a Professor in the Department of Clinical Sciences at Colorado State University.  His lab investigates immune responses in infectious diseases, cancer and allergic and autoimmune diseases.  His lab is currently studying the immune modulatory effects of mesenchymal stem cells (MSC) and the use of MSC to treat chronic kidney disease, chronic liver disease, and chronic wound infections in dogs and cats.  More recently, the lab has also begun developing induced pluripotent stem cell lines (iPSC) from canines, felines, and equines for use in regenerative medicine studies.

Felix Duerr

​Dr. Duerr is an Assistant Professor in the Department of Clinical Sciences at Colorado State University. His group studies new approaches to treatment and rehabilitation of canine sports related injuries and chronic orthopedic conditions in dogs. He is also involved in ongoing investigations of new stem cell approaches to management of chronic osteoarthritis in dogs.

​Dr. Ehrhart is a Professor in the Animal Cancer Center in the Department of Clinical Sciences at Colorado State University.  Her laboratory investigates new approaches to improve bone healing for application to radiation therapy and bone cancer treatment.  Current projects include the use of local or systemic administration of mesenchymal stem cells to stimulate healing of allogeneic bone grafts following bone cancer surgery.

​Dr. Johnson is a post-DVM fellow in the Department of Microbiology, Immunology, and Pathology.  Her work is investigating the antimicrobial properties of activated mesenchymal stem cells and how they induce bacterial killing and enhance antibiotic activity in treatment of chronic infections.  She is currently conducting a clinical trial of activated MSC therapy for dogs with chronic, drug-resistant bacterial infections.

Mercedes Gonzales Juarrero

​Dr. Gonzales-Juarrero studies immunity to tuberculosis and the role of host immune defenses in the lungs. She also studies new lung drug delivey approaches to improve immunity to TB and to hasten lesion clearance in infected individuals.

Dr. Goodrich is an Associate Professor in the Department of Clinical Sciences at Colorado State University.  Her laboratory studies new approaches to bone and joint healing in equine atheletes, including gene therapy and stem cell therapy.  Her lab is currently investigating the use of gene modified mesenchymal stem cells to suppress joint inflammation in joint disease in horses.​

Dr. Guth is an Assistant Professor in the Department of Clinical Sciences  and Animal Cancer Center ​at Colorado State University.  She is currently investigating immunotherapeutic approaches to cancer treatment.  Among her projects is a studying investigating the use of cancer stem cell vaccines as a new approach to cancer immunotherapy.

Dr. Kisiday is an Associate Professor in the Department of Clinical Sciences at Colorado State University.  His laboratory studies factors that regulate the maturation of mesenchymal stem cells into functional cartilage and bone tissues.  His studies investigate the influence of substrates and specific growth factors on the mechanical properties of the regenerating mesenchymal stem cells.

​Dr. Koch is a Professor in the Department of Dermatology at the University of Colorado Denver and the Gates Center for Regenerative Medicine and Stem Cell Biology.  His laboratory focuses on understanding the genetic basis of inherited skin disorders in humans.  The Koch group also uses iPSC technology to investigate new genetic approaches to reversing the defects in genetic skin disorders. 

Michael Lappin, DVM

​Dr. Lappin is a Professor in the Department of Clinical Sciences at Colorado State University.  His laboratory studies immune responses to vaccination against respiratory viruses in cats, as well as immune responses to feline vaccines.  He also oversees a large diagnostic service for feline infectious diseases, including toxoplasmosis, Bartonella, Ehrlichia, and other infectious agents of cats.

Dr. Orton is a Professor in the Department of Clinical Sciences and the Director of the Animal Heart Center at Colorado State University.  His group studies the pathogenesis of valvular heart disease in dogs and humans.  His laboratory also uses new approaches to inhibit immune responses against xenogeneic heart valves.

Dan Regan, DVM

​Dr. Regan is an Assistant Professor in the Department of Microbiology, Immunology, and Pathology and the Animal Cancer Center. He is currently investigating monocyte targeted therapeutics for enhancing cancer vaccine effectiveness and suppressing the growth of tumor metastases, using both mouse models and clinical studies in dogs with cancer.​

Dr. Webb is a Research Scientist in the Department of Clinical Sciences.  She investigates the use of mesenchymal stem cells for suppressing airway inflammation in mouse asthma models.  In addition, she investigates the mechanisms by which mesenchymal stem cells suppress T cell responses in mice and cats.

William Wheat

​Dr. Wheat investigates the role of dendritic cells in the host immune response to vector-borne pathogens. He also studies the impact of mesenchymal stem cells on DC function, and the role of DC in host immunity to inhaled pathogens and immunotherapies.​​

Dr. Zabel is a Professor in the Department of Microbiology, Immunology, and Pathology at Colorado State University.  His laboratory investigates the immune pathogenesis of prion diseases, specifically chronic wasting disease, and how complement proteins and white blood cells facilitate the spread of the organism.  In addition, his laboratory investigates novel immune therapeutic approaches to controlling prion infection in the brain, using mouse models of infection.​

 

 CIRM Associate Members

 

Dylan is a DVM/PhD candidate investigating how macrophage function and metabolism is altered in the tumor microenvironment. He is also working on a project to better understand how immunotherapies can be used to influence macrophage functionality.​​

Lori is working with Dr. Guth in the Cancer Immunotherapy Laboratory to establish new canine cancer cells lines from primary tumors in dogs as well as developing cancer stem cell vaccines for use in canine clinical trials. She is also working to determine effective drug treatment combinations with immune checkpoint molecules and their effect on tumor growth. 

DVM/PhD Student​

​Lyndah is currently working with Dr. Dow in the Regenerative Medicine Laboratory to determine optimal methods for generation of iPSC from tissues of dogs, cats, and horses.  These cells are in turn being investigated for their ability to be differentiated into cells that can be used to regenerate organs such as the liver, kidney, and spinal cord.

​Laura is working with Dr. Ehrhart in the Laboratory of Musculoskeletal Oncology and Traumatology to investigate the effectiveness of MSC therapy for stimulation of bone healing in animals and humans undergoing massive limb allograft procedures. 

Jonathan is working with Dr. Dow in the Regenerative Medicine Laboratory to investigate the immunological properties of MSC and how they suppress T cell proliferation.​

​​Clinical Pathology Resident

Misha is working with Dr. Johnson in the Regenerative Medicine Laboratory growing and characterizing mesenchymal stem cells from exotic species to study their antimicrobial and wound healing properties. She also grows dog mesenchymal stem cells for use in canine clinical trials.​

Sophie is working with Dr. Dow in the Cancer Immunotherapy Laboratory developing assays to examine novel cellular and molecule based immunotherapies for the treatment of cancer in dogs. She is also investigating the role of mitochondrial function in tumor associated macrophages.​

​​

Renata is working with Dr.Dow to develop assays to evaluate the antimicrobial effects and properties ofmesenchymal stem cell that show promise for human clinical trials. She also isinvolved in the screening and evaluation of potential drug treatments and cancer vaccines for use in canine clinical trials. ​

​​

Amy Zug

Jade helps to develop new immunoassays to assess immune responses to cancer stem cell vaccines. She also develops new approaches to generation of mesenchymas stem cells for antimicrobial therapy

Darrin is working with Dr. Johnson in the Regenerative Medicine Laboratory growing mesenchymal stem cells to investigate their antimicrobial and wound healing properties through canine clinical trials. ​

​Dr. Soontararak is a post-doctoral fellow investigating the use of mesenchymal stem cells for immune modulation in animal models of inflammatory bowel disease.​

make a gift
Contact Us:
​1678 Campus Delivery
Fort Collins, Colorado 80523-1678

Phone:
(970) 297-1274 

Fax:
(970) 297-1275