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Dr. Richard Bowen
Office: W113 ARBL Building, Foothills Campus
Phone: 970-491-5768
Fax: 970-491-3557
Richard A. Bowen, DVM, PhD

​Professor, Department of Biomedical Sciences
Animal Reproduction and Biotechnology Laboratory
Colorado State University 


DVM, Colorado State University
MS, Colorado State University
PhD, Colorado State University

Teaching Activities

I teach physiology, genetics and biotechnology to veterinary students. I also work on a project to create a comprehensive Web-based hypertext for use in teaching pathophysiology.

Research Interests -- Infectious Disease

My current interests focus on viral diseases that affect domestic and wild animals and spillover into human populations. Current projects include:

  • Working to understand the pathogenesis of West Nile virus infection in domestic animals, birds and reptiles, and to develop and test vaccines to protect against that disease.
  • Determining vertebrate and mosquito host competency for Japanese encephalitis, and elucidating the pathogenesis of infection in those creatures.
  • Evaluating the potential role of bats in transmission of a number of viruses.
  • Understanding the human-animal interface as it relates to transmission of avian influenza viruses.
  • I serve as Director of the Animal Models Core, and in the capacity supervise numerous trials to evaluate vaccines and therapeutics to protect against a broad range of pathogens.

Representative Publications

For a complete list of publications, please visit: RA Bowen PubMed

Adney DR, Letko M, Ragan IK, Scott D, van Doremalen N, Bowen RA, Munster VJ. Bactrian camels shed large quantities of Middle East Respiratory Syndrome coronavirus (MERS-CoV) after experimental infection. Emerg Microbes Infect 2019; 8:717-723.
Rhyan J, Nol P, Wehtje M, Bosco-Lauth A, Marlenee N, McCollum M, Bruce S, Hartwig A, Steltling S, Robbe-Austerman S, Bowen RA.  Of mice and elk: Partial protection in Balb/c mice and Rocky Mountain Elk (Cervus canadensis) from Brucella abortus infection after vaccination with a killed, mucosally-delivered vaccine.  J Wildlife Dis 2019; April 2019 [Epub ahead of print].
Karna AK, Bowen RA. Experimental evaluation of the role of ecologically-relevant hosts and vectors in Japanese encephalitis virus genotype displacement.  Viruses 2019; doi:10.3390/v11010032.
Lamuka PO, Njeruh FM, Gitao GC, Matofari J, Bowen R, Abey KA. Prevalence of bovine and avian tuberculosis in camel herds and associated public health risk factors in Isiolo County, Kenya.  Trop An Health Prod 2018;
Jia Q, Bowen RA, Dillon BJ, Maslesa-Galic S, Chang BT, Kaidi AC, Horwitz MA. Single vector platform vaccine protects against lethal respiratory challenge with Tier I agents of anthrax, plague, and tularemia.  Sci Reports 2018; 8:7009. doi:10.1038/s41598-018-24581-y.
Bosco-Lauth AM, Hartwig AE, Bowen RA.  Reptiles and amphibians as potential reservoir hosts of chikungunya virus.  Am J Trop Med Hyg 2018; 93:841-844.
Higgins JL, Gonzalez-Juarrero M, Bowen RA.  Evaluation of shedding, tissue burdens, and humoral immune response in goats after experimental challenge with the virulent Brucella melitensis strain 16M and the reduced virulence vaccine strain Rev. 1.  PLoS One 2017; 12:e0185823.
Gaire TN, Karki S, Dhakal IP, Khanal DR, Bowen RA. Serosurveillance and associated factors for antibody presence against bluetongue virus in dairy cattle in two eco-zones of Nepal.  Rev Sci Tech 2016; 35:779-785.
Adney DR, Brown VR, Porter SM, Bielefeldt-Ohmann H, Hartwig AE, Bowen RA.  Inoculation of goats, sheep, and horses with MERS-CoV does not result in productive viral shedding. Viruses 2016; 8:230; doi:10.3390/v8080230.
Chaulagain R, Bowen RA.  Seroprevalence and epidemiological study of bovine brucellosis in dairy cattle of Kavrepalanchowk district of Nepal.  Nepalese J Ag Sci 2016; 14:123-131.
Ragan et al.  IK, Blizzard EL, Gordy P, Bowen RA.  Investigating the potential role of North American animals as hosts for Zika virus.  Vector Borne Zoonotic Dis 2017; 17:161-164.
Bielefeldt-Ohmann H, Bosco-Lauth A, Hartwig A, Uddin MJ, Barcelon J, Suen WW, Wang W, Hall RA, Bowen RA. Characterization of non-lethal West Nile virus (WNV) infection in horses: subclinical pathology and innate immune response.  Microb Pathogenesis 2017; 103:71-79.
Adney DR, Bielefeldt-Ohmann H, Hartwig AE, Bowen RA. Experimental infection and transmission of MERS-CoV in alpacas (Vicugna pacos).  Emerg Infect Dis 2016; 22:1031-1037.

Adney DR, van Doremalen N, Brown VR, Bushmaker T, Scott D, de Wit E, Bowen RA, Munster VJ.  Replication and shedding of MERS-CoV in upper respiratory tract of inoculated dromedary camels.  Emerg Infect Dis 2014; 20:1999-2005.

Achenbach JE, Bowen RA.
The effect of oseltamivir carboxylate consumption on the emergence of drug resistant H5N2 avian influenza virus in mallard ducks.  Antimicrob Agents Chemother 2013; 57:2171-2181.
Baeten LA, Pappert R, Young J, Schriefer ME, Gidlewski T, Kohler D, Bowen RA.  Immunological and clinical response of coyotes (Canis latrans) to experimental inoculation with Yersinia pestis.  J Wildlife Dis 2013; 49:932-939.
Bosco-Lauth AM, Bowen RA.  Biological significance of bats as a natural reservoir of emerging viruses.  In: Viral Infections and Global Change, SK Singh (ed.), Wiley Blackwell, 2014, pp. 195-206.
Cleton NB, Bosco-Lauth A, Page MJ, Bowen RA.  Age-related susceptibility to Japanese encephalitis virus in domestic ducklings and chicks. Am J Trop Med Hyg 2014; 90:242-246.
O’Shea TJ, Bowen RA, Stanley TR, Shankar V, Rupprecht CE.  Variability in seroprevalence of rabies virus neutralizing antibodies and associated factors in a Colorado population of big brown bats (Eptesicus fuscus).  PLoS One 2014; 9:e86261.
Soffler C, Bosco-Lauth AM, Aboellial TA, Marlof AJ, Bowen RA.  Pathogenesis of percutaneous infection of goats with Burkholderia pseudomallei: clinical, pathologic, and immunologic responses in chronic melioidosis.  Internat J Expt Pathol 2014; 95:101-119.
Bowen RA, Bosco-Lauth A, Syvrud K, Thomas A, Meinert TR, Ludlow DR, Cook C, Salt J, Ons E.  Protection of horses from West Nile virus lineage 2 challenge following immunization with a whole, inactivated WNV lineage 1 vaccine.  Vaccine 2014; 32:5455-9.
Brown VR, Adney DR, Bielefeldt-Ohmann H, Gordy PW, Felix TA, Olea-Popelka FJ, Bowen RA.  Pathogenesis and immune responses of Francisella tularensis strains in wild-caught cottontail rabbits.  J Wildlife Dis 2015; 51:564-575.
Bosco-Lauth AM, Han S, Hartwig A, Bowen RA.  Development of a hamster model for chikungunya virus infection and pathogenesis.  PLoS One 2015; DOI:10.1371/journal.pone.0130150.
Brown VR, Adney DR, Olea-Popelka F, Bowen RA.  Prior Inoculation with type B strains of Francisella tularensis provides partial protection against virulent type A strains in cottontail rabbits.  PLoS One 2015; 10:e014073.
Root JJ, Bosco-Lauth AM, Bielefeldt-Ohmann H, Bowen RA.  Experimental infection of peridomestic mammals with emergent H7N9 (A/Anhui/1/2013) influenza A virus: Implications for biosecurity and wet markets.  Virology 2016; 487:242-248.
Borucki MK, Lao V, Hwang M, Gardner S, Adney D, Munster V, Bowen R, Allen JE.  Middle East Respiratory syndrome coronavirus intra-host populations are characterized by numerous high frequency variants. PLoS One. 2016; 11: e0146251.
Bosco-Lauth, AM, Nemeth NM, Kohler DK, Bowen RA.  Viremia in North American mammals and birds following experimental infection with chikungunya viruses.  Am J Trop Med Hyg 2016; 94:504-506.