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Office: W326 Anatomy/Zoology Building
Phone: 970-491-3801
Fax: 970-491-7907
Email: leslie.stone-roy@colostate.edu

Leslie Stone-Roy

​Assistant Professor, Department of Biomedical Sciences
Colorado State University

Education


PhD, University of Colorado Health Sciences Center

Member


Program in Molecular, Cellular and Integrative Neurosciences (MCIN)
Colorado Alliance for Graduate Education and the Professoriate (AGEP)
Front Range Neuroscience Group
Faculty for Undergraduate Neuroscience
Society for Neuroscience
Nu Rho Psi - national honor society in neuroscience
 

Teaching Activities


I teach a variety of topics in neuroscience to undergraduate and graduate students.  My primary teaching responsibilities include providing lectures in Functional Neuroanatomy (BMS 345), Introduction to Cellular Neurobiology (BMS 325), Mammalian Physiology I (BMS 500), Neuronal Circuits, Systems and Behavior (BMS/NB 505).  Beginning in spring of 2015, I will also coordinate and teach a new course in neurobiology: Introduction to Systems Neurobiology (BMS 425).  I also contribute to the laboratory portion of BMS 345 and contribute to the coordination of journal clubs.  Outside of the classroom, I mentor undergraduate and graduate students in my research program and also mentor undergraduate students involved with the Honor’s program and the Presidential Leadership Program at CSU. 

Research Interests


My research efforts focus on the sense of taste and mechanosensation of the tongue.  This research includes investigating the embryonic origins of taste receptor cells and the transduction mechanisms used by individual taste cells.  Recent projects include characterization of peptides and signaling molecules in taste buds from obese mouse models relative to healthy mice of normal weight.  In addition, I am currently collaborating on a project investigating the 2 point discrimination capability of the tongue surface in healthy adult people.

Outreach Activities


I strongly believe in giving back to the Fort Collins community and because of this, I do a substantial amount of outreach in the form of neuroscience presentations to local students ranging from preschool through high school.  My largest annual effort is the coordination of Brain Awareness Week for our community.  For this project, I recruit and train approximately 70 CSU students to present interactive stations covering a variety of neuroscience topics at local high schools.  In addition to this large event, I also visit schools individually throughout the year to talk to students about neurobiology, sensory systems and brain anatomy.  Other efforts include volunteering annually to judge posters for elementary science fairs in the Poudre School District.  This year, I am also a CAS advisor for 5 high school students enrolled in the International Baccalaureate program at Poudre High School.

Featured Publications


Moritz Jr. J, Turk P, Williams JD, and Stone-Roy LM (2017) Perceived Intensity and Discrimination Ability for Lingual Electrotactile Stimulation Depends on Location and Orientation of Electrodes. Front. Hum. Neurosci. 11:186. doi: 10.3389/fnhum.2017.00186

Huang Y.A., Stone L.M., Pereira E., Yang R., Kinnamon J.C., Dvorvanchikov G., Chaudhari N., Finger T.E., Kinnamon S.C. and Roper S.D. (2011) Knocking out P2X receptors reduces transmitter secretion in taste buds. J Neurosci. 31(38):13654-61.

Vandenbeuch A., Tizzano M., Anderson C.B., Stone L.M., Goldberg D., Kinnamon, S.C. (2010) Evidence for a role of glutamate as an efferent transmitter in taste buds. BMC Neurosci. 11:77.

Stone, L.M., Barrows, J., Finger T.E. and Kinnamon, S.C. (2007) Expression of T1Rs and Gustducin in Palatal Taste Buds of Mice.  Chem Senses. 32(3):255-262.

Finger, T.E., Danilova, V. Barrows, J., Bartel, D.L., Vigers, A.J., Stone, L., Hellekant, G. and Kinnamon, S.C. (2005) ATP signaling is crucial for communication from taste buds to gustatory nerves. Science. 310:1495-1499.

Stone, L.M., Tan, S-S., Tam, P.P.L. and Finger, T.E.. (2002) Analysis of cell lineage relationships in taste buds. J Neurosci. 22(11): 4522-4529.

Stone, L.M., Wilcox, C.L. and Kinnamon, S.C. (2002) Virus mediated transfer of foreign DNA into taste receptor cells. Chem  Senses. 27:779-787.

Clapp, T.R., Stone, L.M., Margolskee, R.F. and Kinnamon, S.C. (2001) Immunocytochemical evidence for co-expression of Type III IP3 receptor with signaling components of bitter taste transduction.  BMC Neurosci. 2:6-14.

Stone, L.M., Finger, T.E., Tam, P.P.L. and Tan, S-S. (1995) Taste receptor cells arise from local epithelium, not neurogenic ectoderm. Proc Nat Acad Sci., USA.  92:1916-1920.

Stone, L.M., Browning, M.D. and Finger, T.E. (1994) Differential distribution of synapsins in the olfactory bulb. J Neurosci. 14(1):301-309.

Positions and Employment


1996-2006, Posdoctoral Fellow, Department of Anatomy and Neurobiology, CSU, Fort Collins, CO

2006-2010, Research Scientist / Scholar III, Department of Biomedical Sciences, Colorado State University, Fort Collins, CO

2013, Consultant for Department of Otolaryngology, University of Colorado Denver Anschutz Medical Campus, Aurora, CO

2010-present, Special Assistant Professor, Department of Biomedical Sciences, Colorado State University, Fort Collins, CO

Other Experience


1987-1988, Veterinary Technician, Golden Animal Hospital, Golden, CO

1990, Veterinary Technician, The Eye Clinic, Lakewood, CO

1988-1990, Veterinary Technician, Animal Emergency Services, Lakewood, CO

1995- present, Manuscript reviewer for various neuroscience and biomedical journals, poster judge for regional and local scientific meetings

Honors and Awards


Soo-Kyung Oh Research Award, Univ. of Colo. Health Sciences Center, 1995; Tucker Award, Association for Chemoreception Sciences, 1995; National Research Service Award #F32-DC 00287, 1997-2000; CVMBS College Research Council Award, Colorado State, 2011-2012; Experiential Learning Award, CVMBS, Colorado State University, 2012-2013; CVMBS College Research Council Award, Colorado State, 2013-2014; Microscopy Pilot Project Program Award, 2013-2014