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Images of spermatozoa

 Images of sperm from animals that were exposed to environmental pollutants.

Reproductive Toxicology

​ARBL faculty members have been investigating the developmental and long-term reproductive consequences of perinatal exposure to ubiquitous pollutants using mammalian and amphibian models. 

Several recent reports indicate deteriorating trends in optimal reproduction in the human male, particularly in the industrialized world. Common pollutants having hormone-mimicking capabilities have been implicated in these phenomena. The compounds being studied include:

  • anti-androgen pesticides (DDT and its metabolites; vinclozolin)
  • water disinfection by-products (dibromoacetic acid, bromochloroacetic acid)
  • detergents (alkyl phenols)
  • plasticizers (phthalates

Two aspects of male reproductive function have been studied: sexual function and efficiency and quality of spermatogenesis.

Learn more about the work our faculty are doing by visiting our faculty profile pages.